54 research outputs found
Quantitative Regular Expressions for Arrhythmia Detection Algorithms
Motivated by the problem of verifying the correctness of arrhythmia-detection
algorithms, we present a formalization of these algorithms in the language of
Quantitative Regular Expressions. QREs are a flexible formal language for
specifying complex numerical queries over data streams, with provable runtime
and memory consumption guarantees. The medical-device algorithms of interest
include peak detection (where a peak in a cardiac signal indicates a heartbeat)
and various discriminators, each of which uses a feature of the cardiac signal
to distinguish fatal from non-fatal arrhythmias. Expressing these algorithms'
desired output in current temporal logics, and implementing them via monitor
synthesis, is cumbersome, error-prone, computationally expensive, and sometimes
infeasible.
In contrast, we show that a range of peak detectors (in both the time and
wavelet domains) and various discriminators at the heart of today's
arrhythmia-detection devices are easily expressible in QREs. The fact that one
formalism (QREs) is used to describe the desired end-to-end operation of an
arrhythmia detector opens the way to formal analysis and rigorous testing of
these detectors' correctness and performance. Such analysis could alleviate the
regulatory burden on device developers when modifying their algorithms. The
performance of the peak-detection QREs is demonstrated by running them on real
patient data, on which they yield results on par with those provided by a
cardiologist.Comment: CMSB 2017: 15th Conference on Computational Methods for Systems
Biolog
Efficient Online Timed Pattern Matching by Automata-Based Skipping
The timed pattern matching problem is an actively studied topic because of
its relevance in monitoring of real-time systems. There one is given a log
and a specification (given by a timed word and a timed automaton
in this paper), and one wishes to return the set of intervals for which the log
, when restricted to the interval, satisfies the specification
. In our previous work we presented an efficient timed pattern
matching algorithm: it adopts a skipping mechanism inspired by the classic
Boyer--Moore (BM) string matching algorithm. In this work we tackle the problem
of online timed pattern matching, towards embedded applications where it is
vital to process a vast amount of incoming data in a timely manner.
Specifically, we start with the Franek-Jennings-Smyth (FJS) string matching
algorithm---a recent variant of the BM algorithm---and extend it to timed
pattern matching. Our experiments indicate the efficiency of our FJS-type
algorithm in online and offline timed pattern matching
EndCap Module Production for the ATLAS Silicon Tracker (SCT) at CERN and the University of Geneva
This note describes the infrastructure, procedure and quality assurance for the construction of approximately one third of the EndCap modules for the ATLAS Semiconductor Tracker (SCT) by groups at the University of Geneva and CERN
Search for the exotic resonance in the NOMAD experiment
A search for exotic Theta baryon via Theta -> proton +Ks decay mode in the
NOMAD muon neutrino DIS data is reported. The special background generation
procedure was developed. The proton identification criteria are tuned to
maximize the sensitivity to the Theta signal as a function of xF which allows
to study the Theta production mechanism. We do not observe any evidence for the
Theta state in the NOMAD data. We provide an upper limit on Theta production
rate at 90% CL as 2.13 per 1000 of neutrino interactions.Comment: Accepted to European Physics Journal
Final NOMAD results on nu_mu->nu_tau and nu_e->nu_tau oscillations including a new search for nu_tau appearance using hadronic tau decays
Results from the nu_tau appearance search in a neutrino beam using the full
NOMAD data sample are reported. A new analysis unifies all the hadronic tau
decays, significantly improving the overall sensitivity of the experiment to
oscillations. The "blind analysis" of all topologies yields no evidence for an
oscillation signal. In the two-family oscillation scenario, this sets a 90%
C.L. allowed region in the sin^2(2theta)-Delta m^2 plane which includes
sin^2(2theta)<3.3 x 10^{-4} at large Delta m^2 and Delta m^2 < 0.7 eV^2/c^4 at
sin^2(2theta)=1. The corresponding contour in the nu_e->nu_tau oscillation
hypothesis results in sin^2(2theta)<1.5 x 10^{-2} at large Delta m^2 and Delta
m^2 < 5.9 eV^2/c^4 at sin^2(2theta)=1. We also derive limits on effective
couplings of the tau lepton to nu_mu or nu_e.Comment: 46 pages, 16 figures, Latex, to appear on Nucl. Phys.
Prediction of Neutrino Fluxes in the NOMAD Experiment
The method developed for the calculation of the flux and composition of the
West Area Neutrino Beam used by NOMAD in its search for neutrino oscillations
is described. The calculation is based on particle production rates computed
using a recent version of FLUKA and modified to take into account the cross
sections measured by the SPY and NA20 experiments. These particles are
propagated through the beam line taking into account the material and magnetic
fields they traverse. The neutrinos produced through their decays are tracked
to the NOMAD detector. The fluxes of the four neutrino flavours at NOMAD are
predicted with an uncertainty of about 8% for nu(mu) and nu(e), 10% for
antinu(mu), and 12% for antinu(e). The energy-dependent uncertainty achieved on
the R(e, mu) prediction needed for a nu(mu)->nu(e) oscillation search ranges
from 4% to 7%, whereas the overall normalization uncertainty on this ratio is
4.2%.Comment: 43 pages, 20 figures. Submitted to Nucl. Phys.
A Study of Strange Particles Produced in Neutrino Neutral Current Interactions in the NOMAD Experiment
Results of a detailed study of strange particle production in neutrino
neutral current interactions are presented using the data from the NOMAD
experiment. Integral yields of neutral strange particles (K0s, Lambda,
Lambda-bar) have been measured. Decays of resonances and heavy hyperons with an
identified K0s or Lambda in the final state have been analyzed. Clear signals
corresponding to K* and Sigma(1385) have been observed. First results on the
measurements of the Lambda polarization in neutral current interactions have
been obtained.Comment: Accepted for publication in Nuclear Physics B as a rapid
communicatio
Search for nu(mu)-->nu(e) Oscillations in the NOMAD Experiment
We present the results of a search for nu(mu)-->nu(e) oscillations in the
NOMAD experiment at CERN. The experiment looked for the appearance of nu(e) in
a predominantly nu(mu) wide-band neutrino beam at the CERN SPS. No evidence for
oscillations was found. The 90% confidence limits obtained are delta m^2 < 0.4
eV^2 for maximal mixing and sin^2(2theta) < 1.4x10^{-3} for large delta m^2.
This result excludes the LSND allowed region of oscillation parameters with
delta m^2 > 10 eV^2.Comment: 19 pages, 8 figures. Submitted to Phys. Lett.
A study of backward going and in interactions with the NOMAD detector
Backward proton and production has been studied in
interactions with carbon nuclei. Detailed analyses of the momentum
distributions, of the production rates, and of the general features of events
with a backward going particle, have been carried out in order to understand
the mechanism producing these particles. The backward proton data have been
compared with the predictions of the reinteraction and the short range
correlation models.Comment: 29 pages, 14 figures, submitted to Nucl. Phys.
Inclusive production of and mesons in charged current interactions
The inclusive production of the meson resonances ,
and in neutrino-nucleus charged current interactions has been
studied with the NOMAD detector exposed to the wide band neutrino beam
generated by 450 GeV protons at the CERN SPS. For the first time the
meson is observed in neutrino interactions. The statistical
significance of its observation is 6 standard deviations. The presence of
in neutrino interactions is reliably established. The average
multiplicity of these three resonances is measured as a function of several
kinematic variables. The experimental results are compared to the
multiplicities obtained from a simulation based on the Lund model. In addition,
the average multiplicity of in antineutrino - nucleus
interactions is measured.Comment: 23 pages, 14 figures, 8 tables. To appear in Nucl. Phys.
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